Team Hugues DUFFAU – Jean-Philippe HUGNOT
Brain plasticity, stem cells and diffuse low-grade gliomas
Project Bio-molecular characterization of meningiomas
PRINCIPAL INVESTIGATOR
IGF staff involved
Valérie RIGAU
PU-PH, UM
Meningiomas are the most common primary intracranial tumours. Generally perceived as benign tumours, they are nonetheless associated with significant morbidity due to the symptoms associated with their natural history or the morbidity of the treatments used. Our team is focusing on the search for markers to better define the prognosis of these tumours, as well as the possibility of introducing targeted treatments against certain somatic mutations present in skull base meningiomas. Current projects are focusing on the development of prognostic markers detectable in serum to better guide the management of patients with meningiomas.
Meningioma image
Main publications
• Boetto., et al. (2023) Acta Neuropath, 146 (6) :833-835.
• Boetto., et al. (2022) Neurosurg, 92(2)391-397.
• Boetto., et al. (2021) Neuropathol Apl Neurobiol, 47(6)748-755.
Funding
• 2022: Fondation de l’Avenir
• 2021: Poste d’accueil INSERM
Collaborations
• Michel Kalamarides (Paris)
• Catherine Panabières (Montpellier)
• Felix Sahm, (Heidelberg)
