CLEVER : Rebalancing gluCose utiLization in vulnErability to chronic stress: a noVel stratEgy to promote Resiliency against psychopathology
An IGF team leads the European CLEVER consortium aiming to elucidate the metabolomics of vulnerability to depression and resilience to treatments.
The National Research Agency has joined forces with the ERA-NET NEURON COFUND 2, a financing platform focused on neurological and mental disorders, to finance from 2024 the transnational project on the Mechanisms of Resilience and Vulnerability to Mental Health Stressors. Freddy Jeanneteau at the IGF leads the European CLEVER consortium aimed specifically at understanding the link between epigenetics and metabolomics in treatment-resistant depressed patients and preclinical models differentiating subjects who are vulnerable and resilient to depressive disorders.
The consortium is working on the hypothesis that the type of fuel used by the brain may differentiate between vulnerability and resilience to stress-related mental illnesses.
The consortium also includes two German teams, an Italian team and a Polish team. The consortium is recruiting young researchers from France, Italy and Germany.
